![]() ![]() "If you were ever to be exposed to the infection again, your body would basically be able to respond quickly and more robustly that second time around," he added. Vivek Cherian, an internal-medicine physician in Baltimore, told Insider. "If you've already had a COVID-19 infection, you've developed memory cells from that infection," Dr. About 73% of vaccine recipients who'd previously had COVID-19 developed side effects after dose one of Pfizer-BioNTech's or Moderna's shot, compared with 66% of vaccine recipients who'd never gotten infected. People who've had COVID-19 may develop more side effects after dose 1Ī small study from the Icahn School of Medicine at Mount Sinai found that vaccine side effects such as fatigue, headaches, and chills were more common among people with preexisting immunity to the coronavirus than people who'd never been infected. Fevers were also far more common among second-dose recipients than first-dose recipients in both trials. In Moderna's trial, meanwhile, about five times as many participants developed chills after their second dose as did after their first. ![]() Roughly twice as many participants in Pfizer's trial developed chills and joint pain after their second dose than after their first. Dose 2 usually comes with more severe side effectsįor those who haven't had COVID-19 before, side effects tend to be more numerous and severe after the second dose. Clinical trials suggest that side effects are generally more pronounced among women and younger adults, especially after their second dose. While doctors can't predict exactly how someone will respond to a coronavirus vaccine, they've identified a few patterns based on a person's age, sex, health status, and which dose they're receiving. ![]() "It was really just that first day of feeling achy and flu-y," Baird told Insider. On average, however, people typically feel more run-down after their second shot.īaird's age complicated her expectations: She's 56, and clinical trials have shown that people over 55 often develop fewer vaccine side effects. Many people who've had a prior infection develop more side effects in response to the first vaccine dose than the second. When Freedom Baird got her first dose of Moderna's vaccine in February, she wasn't sure what kind of side effects to anticipate.īaird is a COVID-19 long-hauler - she's had lingering shortness of breath and chest pain for roughly a year. See more stories on Insider's business page. Side effects are generally more pronounced after the second dose than the first. Women and younger adults tend to have more side effects than men or older adults do. Jessica Christian/The San Francisco Chronicle/Getty ImagesĬOVID-19 vaccine side effects can vary depending on a person's age, sex, or health. Rose Hospital in Hayward, California, on January 8. Alameda County workers lined up to receive coronavirus vaccines outside St. ![]()
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